Abstract. Objective. To compare the efficacy and safety of intra-articular triamcinolone hexacetonide (TH) and triamcinolone acetonide (TA) in children with ol. Name: Triamcinolone hexacetonide; Drug Entry: Triamcinolone. A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local. The intralesional administration of Aristospan (triamcinolone hexacetonide injectable suspension, USP) 5 mg/mL is indicated for alopecia areata; discoid lupus.


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Triamcinolone hexacetonide, laboratory and immunological variables were noted triamcinolone hexacetonide order to examine possible factors, other than treatment, predictive of the result. Seventy injections were performed using TH and 60 with TA. The two groups were comparable for clinical, immunological and laboratory characteristics.

Triamcinolone hexacetonide 20 mg/ml suspension for injection

Triamcinolone hexacetonide rate of response was significantly higher with TH than with TA: At comparable doses TH appeared to be much more effective than TA for intra-articular use, in both short- and long-term follow-up.

This result was not affected by disease triamcinolone hexacetonide or degree of local and systemic inflammation.


Juvenile idiopathic arthritis, Intra-articular corticosteroids, Triamcinolone hexacetonide. Intra-articular corticosteroids IACS have been employed for the treatment of rheumatoid arthritis RA in adults since [ 1 ], triamcinolone hexacetonide have recently also become an important therapeutic tool for the treatment of juvenile arthritis.

Triamcinolone hexacetonide

IACS are recommended by some authors as first-line therapy triamcinolone hexacetonide the oligoarticular type of juvenile idiopathic arthritis JIArather than for selective use in active synovitis resistant to non-steroidal anti-inflammatory drugs NSAIDs [ 2 ].

Furthermore, recent data show that early, continued use of IACS may help prevent the development of leg length discrepancies and other triamcinolone hexacetonide in children with JIA [ 34 ]. The beneficial effect and duration triamcinolone hexacetonide effect of single-dose injection are dependent on the preparation used.

Triamcinolone hexacetonide longest-lasting effects have been observed with less soluble compounds [ 56 ]. The choice of preparation is often arbitrary, in many cases depending on where the rheumatologist has been trained triamcinolone hexacetonide 7 ] and on the commercial availability of the drug.

This can be partially explained by the rarity of studies comparing the efficacy of different preparations, particularly in children. To our knowledge, no prospective studies have been performed to date to compare the short- and long-term efficacy of the two most commonly used Triamcinolone hexacetonide drugs, TH and TA, in reducing joint inflammation in children with JIA.

In this prospective study, we compared the efficacy and safety of TH and TA, given intra-articularly, in a cohort of triamcinolone hexacetonide with oligoarticular JIA. Patients and methods Patients The study groups consisted of patients managed at the Paediatric Rheumatology Unit of the University of Padua.


All the patients fulfilled the revised diagnostic criteria for JIA of the persistent or extended oligoarticular types [ 8 ]. Patients triamcinolone hexacetonide had a history of any clinically significant adverse reaction to triamcinolone hexacetonide, ongoing chronic disease or erosive findings on joint X-ray or who had received IACS treatment during the previous 12 months were excluded from the study.

The choice of drug was dependent on the availability of TH during the study period.


TH has to be imported into Italy via neighbouring countries, and sometimes there are shortages of the drug.

Triamcinolone hexacetonide this reason, we have used TA as an alternative long-lasting steroid preparation.

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  • Drug action

We were thus able triamcinolone hexacetonide compare the efficacies of these two drugs. Children were advised not to bear weight for at least 72 h after the injection. This medicinal product must not be administered to infants born recently or prematurely because triamcinolone hexacetonide contains benzyl alcohol.

It may provoke toxic and anaphylactoid reactions in children under 3 years of age.